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Ultrasonic photoacoustic multimode imaging

Seeing More by Listening Is a technique using simultaneous imaging of ultrasonic and photoacoustic waves that can improve the identification of the structure and function of biological tissues. The technology can be used to detect breast cancer, glioma, cardiovascular disease and other diseases. Based on the ultrasonic photoacoustic multi-mode imaging system of Seeing More by Listening technology, this system can achieve high resolution, high contrast and high sensitivity imaging. The system uses a new type of photoacoustic probe that receives both ultrasonic and photoacoustic waves, thereby improving the imaging efficiency and quality. This system was validated in breast cancer models and mouse tumor models and showed excellent imaging performance. Based on Seeing More by Listening technology ultrasonic photoacoustic multi-mode imaging system, this system enables rapid, low-dose and deep imaging. The system adopts a new optical scanning method, which can reduce the laser energy loss and improve the scanning speed. The system was validated in rat skin models and human finger models, showing high resolution and high contrast imaging results.


Reference Documentation:

[1]Wang L V, Hu S. Photoacoustic tomography: in vivo imaging from organelles to organs. Science, 2012, 335(6075): 1458-1462. https://science.sciencemag.org/content/335/6075/1458

[2]Wang L V, Yao J. A practical guide to photoacoustic tomography in the life sciences. Nature Methods, 2016, 13(8): 627-638. https://www.nature.com/articles/nmeth.3925

[3]Li C, Aguirre A, Gamelin J, Maurudis A, Zhu Q, Wang L V. Real-time photoacoustic tomography of cortical hemodynamics in small animals. IEEE Transactions on Biomedical Engineering, 2010, 57(4): 959-962. https://ieeexplore.ieee.org/document/5356729

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