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Intelligent multifunctional micro-nano robot refers to the artificial robot with micron or nano-scale, which can achieve a variety of functions in or outside the organism, such as detection, imaging, delivery, diagnosis, treatment and so on. These robots can use a variety of external stimuli, such as magnetic field, light, acoustic waves, temperature, etc., to control their movement direction and speed, and interact with other machines or biomolecules to achieve the identification and intervention of specific goals within the organism. These robots have the advantages of high efficiency, precision and safety, and can be used in a variety of applications in the biomedical field. Case of intelligent multi-functional micro-nano robot: Micro-and nano-robots based on ferrite nanoparticles (FNP) can realize the magnetron movement and communication in the live body. FNP is loaded on different shapes of silicon-based carriers to form different types of micro-nanorobots, such as disk, rod and spiral. These robots can control their motion direction and speed through an external magnetic field and communicate with other robots or external devices through FNP MR. These robots were used to achieve various functions in the body, including drug delivery, imaging and treatment in mice. Micro-and nano robots based on DNA origami technology can realize light-controlled motion and intelligent response in the live body. Folold DNA molecules into micro-nanorobots with triangular frames and connect different types of functional molecules, such as fluorescent molecules, drug molecules, antibody molecules, at their vertices. These robots can control the direction and speed of their motion through external lasers and achieve intelligent responses with other robots or biological cells through base pairing of DNA molecules. These robots were used to achieve various imaging, diagnostic, and therapeutic functions in mice. Micro-nano robots based on metal-organic framework (MOF) can realize sound-controlled motion and intelligent response in living life. They loaded MOF molecules on a silicon-based carrier with hollow structure to form micro-nanorobots with porous properties. These robots can control their motion direction and speed through external ultrasound waves, and achieve an intelligent response to biomolecules through the adsorption properties of MOF molecules. These robots were used to perform drug delivery and treatment in mice.