HPT-PFs
| 【Numbering】BKMC101003 | 【CAS】CAS | ||
| 【Item No.】BKMC101003-2 | 【specification】 | ||
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Name: HPT-PFs
Composition: HA, TMSP, CD47, and plasmid
Size: 300-500nm
Application: Tumor-associated macrophages
Storage conditions: -4℃
Other instructions: Half a year under sealed state [Main advantage] 1. Due to tumor specific transfection of HPT-PF vector, more than 27% of tumor cells lost CD47 expression after gene editing of HPT-PF, causing swallowing of giant cells; 2. M1 polarized TAM and inflammatory cytokines secretion lead to significant inhibition of tumor growth; 3. The combination of CRISPR-mediated CD47 positive break and IL-12 production in tumor cells can jointly promote macrophage-mediated immunotherapy
Title:CRISPR-based in situ engineering tumor cells to reprogram macrophages for effective cancer immunotherapy
Article link:https://blog.csdn.net/m0_69808569/article/details/124292364
Message
Composition: HA, TMSP, CD47, and plasmid
Size: 300-500nm
Application: Tumor-associated macrophages
Storage conditions: -4℃
Other instructions: Half a year under sealed state [Main advantage] 1. Due to tumor specific transfection of HPT-PF vector, more than 27% of tumor cells lost CD47 expression after gene editing of HPT-PF, causing swallowing of giant cells; 2. M1 polarized TAM and inflammatory cytokines secretion lead to significant inhibition of tumor growth; 3. The combination of CRISPR-mediated CD47 positive break and IL-12 production in tumor cells can jointly promote macrophage-mediated immunotherapy
Title:CRISPR-based in situ engineering tumor cells to reprogram macrophages for effective cancer immunotherapy
Article link:https://blog.csdn.net/m0_69808569/article/details/124292364
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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